SCHEMBL6820262

SCHEMBL6820262

CCCSCc1ccc(O)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.61
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
HIF1A Q16665 4/20 0.47
HSD17B10 Q99714 4/20 0.47
CYP3A4 P08684 3/20 0.47
NFKB1 P19838 3/20 0.47
CYP2D6 P10635 2/20 0.47
DRD2 P14416 2/20 0.47
ADRA1A P35348 2/20 0.47
DRD3 P35462 2/20 0.47
TSHR P16473 2/20 0.47
DRD1 P21728 1/20 0.47
DRD4 P21917 1/20 0.47
DRD5 P21918 1/20 0.47
ADRA1D P25100 1/20 0.47
ADRA1B P35368 1/20 0.47
KDM4E B2RXH2 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6824104 0.89 TRPA1 (0.52) TRPA1CA1CA2CA4CA6
SCHEMBL6918340 0.87 TRPA1 (0.50) TRPA1CA1CA2CA4CA6
SCHEMBL23712633 0.85 TRPA1 (0.42) TRPA1CA2HIF1AHSD17B10CYP3A4
SCHEMBL27839568 0.85 ESR1 (0.55) TRPA1TP53ESR1CNR1AR
SCHEMBL19359681 0.84 TRPA1 (0.59) TRPA1CA1CA2CA4CA6
SCHEMBL28996201 0.83 CA1 (0.61) TRPA1CA1CA2CA4CA6
SCHEMBL6922835 0.80 ALOX15 (0.50) TRPA1CA1CA2CA4CA6
SCHEMBL12432133 0.79 IDO1 (0.41) CYP3A4CYP2D6ALDH1A1RECQLCYP1A2
SCHEMBL27424016 0.78 CYP1A2 (0.48) CA2CYP3A4CYP2D6TSHRALDH1A1
SCHEMBL27820046 0.78 ESR1 (0.45) CA2HIF1AHSD17B10CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004018416-A1 4-[(ALKYLSULFANYL)METHYL]-1, 2-BENZENEDIOL, PREPARATION METHOD THEREOF AND ANTIOXIDANT CONTAINING THE SAME REX BIOSCIENCES INC. (KR) 2004-03-04 WO claimed
WO-2004018416-A1 4-[(ALKYLSULFANYL)METHYL]-1, 2-BENZENEDIOL, PREPARATION METHOD THEREOF AND ANTIOXIDANT CONTAINING THE SAME REX BIOSCIENCES INC. (KR) 2004-03-04 WO disclosed