SCHEMBL6922835

SCHEMBL6922835

CC(C)CCSCc1ccc(O)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 7/20 0.50
ALOX12 P18054 5/20 0.50
KDM4E B2RXH2 4/20 0.50
MAPK1 P28482 4/20 0.50
HIF1A Q16665 4/20 0.50
HSD17B10 Q99714 4/20 0.50
ALDH1A1 P00352 3/20 0.50
CYP3A4 P08684 3/20 0.50
TP53 P04637 3/20 0.50
CYP1A2 P05177 3/20 0.50
NFKB1 P19838 3/20 0.50
THPO P40225 3/20 0.50
MAPT P10636 3/20 0.50
MEN1 O00255 2/20 0.50
ESR1 P03372 2/20 0.50
HPGD P15428 2/20 0.50
RECQL P46063 2/20 0.50
KMT2A Q03164 2/20 0.50
TRPA1 O75762 2/20 0.50
IGF1R P08069 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27820043 0.87 ESR1 (0.50) ALOX15ALOX12KDM4EMAPK1HIF1A
SCHEMBL27839589 0.80 TAAR1 (0.42) MEN1ESR1KMT2ASLC6A2GAA
SCHEMBL6820262 0.80 TRPA1 (0.61) ALOX15ALOX12KDM4EMAPK1HIF1A
SCHEMBL28996201 0.79 CA1 (0.61) ALOX15ALOX12KDM4EMAPK1HIF1A
SCHEMBL6824104 0.77 TRPA1 (0.52) ALOX15ALOX12KDM4EMAPK1HIF1A
SCHEMBL6918340 0.76 TRPA1 (0.50) ALOX15ALOX12KDM4EMAPK1HIF1A
SCHEMBL19359681 0.76 TRPA1 (0.59) ALOX15ALOX12KDM4EMAPK1HIF1A
SCHEMBL1291747 0.76 ALOX15 (0.59) ALOX15ALOX12KDM4EMAPK1HIF1A
SCHEMBL6922690 0.74 ALOX15 (0.57) ALOX15ALOX12KDM4EMAPK1HIF1A
SCHEMBL6570319 0.73 ALOX15 (0.67) ALOX15ALOX12KDM4EMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004018416-A1 4-[(ALKYLSULFANYL)METHYL]-1, 2-BENZENEDIOL, PREPARATION METHOD THEREOF AND ANTIOXIDANT CONTAINING THE SAME REX BIOSCIENCES INC. (KR) 2004-03-04 WO claimed
WO-2004018416-A1 4-[(ALKYLSULFANYL)METHYL]-1, 2-BENZENEDIOL, PREPARATION METHOD THEREOF AND ANTIOXIDANT CONTAINING THE SAME REX BIOSCIENCES INC. (KR) 2004-03-04 WO disclosed