Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 7/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381981 | 0.91 | HTR7 (0.49) | HTR7UTS2RHTR1ADRD2HTR2A | |
| SCHEMBL6824741 | 0.89 | HTR7 (0.47) | HTR7UTS2RHTR1ADRD2HTR2A | |
| SCHEMBL6823392 | 0.89 | HTR7 (0.49) | HTR7UTS2RHTR1ADRD2HTR2A | |
| SCHEMBL6820545 | 0.89 | HTR7 (0.50) | HTR7UTS2RHTR1ADRD2HTR2A | |
| SCHEMBL6823956 | 0.85 | HTR7 (0.47) | HTR7UTS2RHTR1ADRD2HTR2A | |
| SCHEMBL7351045 | 0.84 | HTR7 (0.47) | HTR7UTS2RHTR1AACHE | |
| SCHEMBL6823860 | 0.84 | UTS2R (0.49) | HTR7UTS2RHTR1ADRD2HTR2A | |
| SCHEMBL6823855 | 0.84 | UTS2R (0.49) | HTR7UTS2RHTR1ADRD2HTR2A | |
| SCHEMBL6820576 | 0.84 | UTS2R (0.43) | HTR7UTS2RHTR1ADRD2HTR2A | |
| SCHEMBL6823226 | 0.84 | UTS2R (0.48) | HTR7UTS2RHTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | claimed |
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | disclosed |