Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820986 | 0.86 | HDAC1 (0.47) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL10412116 | 0.83 | NPC1 (0.55) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL10413206 | 0.81 | L3MBTL1 (0.54) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL6820709 | 0.78 | L3MBTL1 (0.54) | MEN1KMT2AALDH1A1HTTNPSR1 | |
| SCHEMBL6700133 | 0.77 | HDAC6 (0.56) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL10413626 | 0.76 | TSHR (0.56) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL6821030 | 0.76 | HDAC1 (0.62) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL30049411 | 0.76 | HDAC1 (0.62) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL29392085 | 0.73 | MEN1 (0.58) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL668767 | 0.73 | MEN1 (0.58) | HDAC1HDAC2HDAC8HDAC6HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |