Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 4/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817368 | 0.85 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1KMT2ABACE1MTNR1A | |
| SCHEMBL4887683 | 0.79 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1KMT2AMTNR1AMTNR1B | |
| SCHEMBL6821068 | 0.78 | HDAC1 (0.50) | ALDH1A1KMT2ATHRBNPSR1MEN1 | |
| SCHEMBL28387470 | 0.77 | ESR1 (0.53) | L3MBTL1ALDH1A1KMT2APTGS2HTT | |
| SCHEMBL9229710 | 0.76 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1KMT2ABACE1MTNR1A | |
| SCHEMBL7799991 | 0.74 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1KMT2ABACE1MTNR1A | |
| SCHEMBL6086162 | 0.74 | PTGS2 (0.71) | L3MBTL1ALDH1A1KMT2AMTNR1AMTNR1B | |
| SCHEMBL16619184 | 0.74 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1KMT2ABACE1MTNR1A | |
| SCHEMBL31413549 | 0.74 | GRIK1 (0.65) | L3MBTL1ALDH1A1KMT2ABACE1MTNR1A | |
| SCHEMBL1171837 | 0.74 | GRIK1 (0.65) | L3MBTL1ALDH1A1KMT2ABACE1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111087391-A | 4-indole quinazoline compound and preparation method and application thereof | 郑州大学 | 2020-05-01 | — | — | CN | disclosed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |