Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2824971 | 0.80 | HDAC6 (0.64) | HDAC6HDAC1HDAC2HDAC8HDAC9 | |
| SCHEMBL30049411 | 0.79 | HDAC1 (0.62) | HDAC6HDAC1HDAC2HDAC8HDAC9 | |
| SCHEMBL6821030 | 0.79 | HDAC1 (0.62) | HDAC6HDAC1HDAC2HDAC8HDAC9 | |
| SCHEMBL6086266 | 0.78 | HDAC1 (0.62) | HDAC6HDAC1HDAC2HDAC8HDAC9 | |
| SCHEMBL20853225 | 0.78 | HDAC1 (0.62) | HDAC6HDAC1HDAC2HDAC8HDAC9 | |
| SCHEMBL6695593 | 0.77 | GALR3 (0.71) | HDAC6HDAC1PPARGMAPTNPC1 | |
| SCHEMBL6695297 | 0.77 | HDAC1 (0.46) | HDAC6HDAC1HDAC2HDAC8HDAC9 | |
| SCHEMBL6087324 | 0.77 | HDAC1 (0.60) | HDAC6HDAC1HDAC2HDAC8HDAC9 | |
| SCHEMBL6821068 | 0.77 | HDAC1 (0.50) | HDAC6HDAC1HDAC2HDAC8HDAC9 | |
| SCHEMBL6225425 | 0.76 | GALR3 (0.69) | HDAC6HDAC1PPARGMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229874-A1 | 5HT7 Antagonists and inverse agonists | PFIZER INC. | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229874-A1 | 5HT7 Antagonists and inverse agonists | HTR7, HTR1A, HTR1B | HDAC6 1841/4885HDAC1 2282/4885HDAC2 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.