Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434421 | 0.78 | KIF11 (0.56) | MEN1MAPTKMT2ARXFP1KIF11 | |
| SCHEMBL5261055 | 0.77 | GPR52 (0.53) | RXFP1EPHX1MAPK8 | |
| SCHEMBL7615106 | 0.75 | KIF11 (0.63) | RXFP1KIF11GRIK1ALDH1A1 | |
| SCHEMBL6821850 | 0.74 | DAO (0.48) | MEN1MAPTKMT2A | |
| SCHEMBL2419022 | 0.72 | L3MBTL1 (0.68) | MEN1MAPTKMT2AALDH1A1HTT | |
| SCHEMBL2577342 | 0.71 | ACP3 (0.49) | MEN1MAPTKMT2A | |
| SCHEMBL27827183 | 0.71 | TAAR1 (0.53) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL11819177 | 0.71 | MEN1 (0.47) | MEN1MAPTKMT2ARXFP1EPHX1 | |
| SCHEMBL12812255 | 0.71 | KDM4E (0.52) | MEN1MAPTKMT2ARXFP1ALDH1A1 | |
| SCHEMBL30370514 | 0.70 | TAAR1 (0.58) | MEN1MAPTKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906273-A1 | PHENYL DERIVATIVES CONTAINING AN ACIDIC GROUP, THEIR PREPARATION AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997045400-A1 | PHENYL DERIVATIVES CONTAINING AN ACIDIC GROUP, THEIR PREPARATION AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1997-12-04 | — | — | WO | disclosed |