Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 11/20 | 0.50 |
| ▸ | DRD2 | P14416 | 10/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7403777 | 0.80 | DRD4 (0.54) | HRH3DRD4DRD2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL6821925 | 0.80 | DRD4 (0.51) | DRD4DRD2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL6821873 | 0.77 | L3MBTL3 (0.53) | DRD4DRD2 | |
| Hydrochloric Acid SCHEMBL13736016 | 0.77 | SIGMAR1 (0.59) | SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL13736012 | 0.77 | SIGMAR1 (0.59) | SIGMAR1HRH3 | |
| SCHEMBL6844227 | 0.77 | DRD4 (0.84) | SIGMAR1DRD4DRD2HTR1AHTR2A | |
| SCHEMBL3587156 | 0.77 | LMNA (0.52) | HRH3DRD4DRD2 | |
| SCHEMBL20766385 | 0.76 | SIGMAR1 (0.73) | SIGMAR1 | |
| SCHEMBL5842536 | 0.73 | HRH3 (0.53) | HRH3 | |
| SCHEMBL15511339 | 0.73 | SIGMAR1 (0.54) | SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056821-A2 | QUINOLIZIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |