Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.34 |
| ▸ | CSK | P41240 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822546 | 0.92 | ADORA1 (0.41) | ADORA1IGF1RCASRCMKLR1ABL1 | |
| SCHEMBL6822608 | 0.90 | CMKLR1 (0.41) | ADORA1CMKLR1ABL1SRC | |
| SCHEMBL6824716 | 0.90 | ADORA1 (0.40) | ADORA1IGF1RADORA2ACMKLR1HRH3 | |
| SCHEMBL6818520 | 0.90 | ADORA1 (0.40) | ADORA1IGF1RADORA2ACMKLR1HRH3 | |
| SCHEMBL6818702 | 0.90 | ADORA1 (0.46) | ADORA1CMKLR1 | |
| SCHEMBL6821959 | 0.89 | ADORA1 (0.42) | ADORA1PTGER1IGF1RCASREGFR | |
| SCHEMBL6822276 | 0.89 | ADORA1 (0.46) | ADORA1TP53POLBIGF1RCMKLR1 | |
| SCHEMBL6822100 | 0.89 | ADORA1 (0.40) | ADORA1IGF1RCMKLR1HRH3 | |
| SCHEMBL6822034 | 0.89 | NPC1 (0.42) | ADORA1PTGER1LMNACMKLR1 | |
| SCHEMBL6822138 | 0.88 | ADORA1 (0.45) | ADORA1ADORA2ASRCHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110763-A1 | Pyrazolopyridine compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110763-A1 | Pyrazolopyridine compound and pharmaceutical use thereof | ADRB1, ADRA1D, ADRB3 | ADORA1 22/4885PTGER1 325/4885LMNA 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.