Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822497 | 1.00 | HPGD (0.43) | HPGDADORA1ADORA2AMEN1NPC1 | |
| SCHEMBL6818751 | 0.99 | ADORA1 (0.42) | HPGDADORA1ADORA2AMEN1NPC1 | |
| SCHEMBL6824296 | 0.92 | ADORA1 (0.41) | ADORA1ADORA2AALDH1A1 | |
| SCHEMBL6818425 | 0.92 | ALDH1A1 (0.46) | HPGDADORA1ADORA2ANPC1ALDH1A1 | |
| SCHEMBL6822103 | 0.89 | HPGD (0.40) | HPGDADORA1ADORA2A | |
| SCHEMBL6822611 | 0.87 | ALDH1A1 (0.47) | HPGDMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL6818544 | 0.87 | ADORA1 (0.46) | HPGDADORA1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL6818692 | 0.86 | HSD17B10 (0.41) | HPGDADORA1MEN1NPC1ALDH1A1 | |
| SCHEMBL6818699 | 0.86 | HSD17B10 (0.41) | HPGDADORA1MEN1NPC1ALDH1A1 | |
| SCHEMBL6822064 | 0.85 | USP2 (0.42) | ADORA1ADORA2AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110763-A1 | Pyrazolopyridine compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110763-A1 | Pyrazolopyridine compound and pharmaceutical use thereof | ADRB1, ADRA1D, ADRB3 | HPGD 684/4885ADORA1 22/4885ADORA2A 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.