Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 7/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824695 | 0.99 | ADORA2A (0.47) | ADORA1ADORA2AMCHR1LTA4HHRH3 | |
| SCHEMBL6821914 | 0.97 | ADORA1 (0.41) | ADORA1ADORA2AMCHR1LTA4HHRH3 | |
| SCHEMBL6822144 | 0.93 | ADORA2A (0.47) | ADORA1ADORA2AMCHR1ADORA3ADORA2B | |
| SCHEMBL6818497 | 0.89 | POLB (0.42) | ADORA1ADORA2AHRH3 | |
| SCHEMBL6821894 | 0.88 | KDM4E (0.40) | ADORA1ADORA2AHRH3KCNH2 | |
| SCHEMBL6822546 | 0.88 | ADORA1 (0.41) | ADORA1HRH3 | |
| SCHEMBL6824716 | 0.87 | ADORA1 (0.40) | ADORA1ADORA2AHRH3ADORA3 | |
| SCHEMBL6818520 | 0.87 | ADORA1 (0.40) | ADORA1ADORA2AHRH3 | |
| SCHEMBL6822544 | 0.86 | L3MBTL1 (0.43) | ADORA1HRH3 | |
| SCHEMBL6822100 | 0.86 | ADORA1 (0.40) | ADORA1MCHR1HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110763-A1 | Pyrazolopyridine compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110763-A1 | Pyrazolopyridine compound and pharmaceutical use thereof | ADRB1, ADRA1D, ADRB3 | ADORA1 22/4885ADORA2A 34/4885MCHR1 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.