SCHEMBL6822147

SCHEMBL6822147

CC(C)(CNC(=O)Nc1ccc(F)c(F)c1)CC(=O)N(CC(=O)NO)CC1CCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.38
DPP4 P27487 1/20 0.38
NAMPT P43490 1/20 0.36
PRMT3 O60678 2/20 0.36
EGFR P00533 1/20 0.36
MET P08581 1/20 0.36
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
POLB P06746 1/20 0.35
EPHX1 P07099 2/20 0.35
EPHX2 P34913 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CCR3 P51677 1/20 0.34
RECQL P46063 1/20 0.34
F10 P00742 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825458 0.90 KLK7 (0.39) SMN1; SMN2NPC1RAB9ADPP4MEN1
SCHEMBL7064641 0.89 NPY2R (0.41) SMN1; SMN2NPC1RAB9AL3MBTL1MEN1
SCHEMBL6822317 0.89 NPY2R (0.41) L3MBTL1MEN1KMT2AEPHX2
SCHEMBL6825283 0.89 KMT2A (0.42) SMN1; SMN2NPC1RAB9AMEN1KMT2A
SCHEMBL6822393 0.88 SLC6A9 (0.42)
SCHEMBL6822389 0.87 MEN1 (0.38) SMN1; SMN2NPC1RAB9AL3MBTL1MEN1
SCHEMBL6825428 0.86 S1PR1 (0.43) NPC1RAB9AL3MBTL1HPGDTSHR
SCHEMBL6825935 0.86 MEN1 (0.41) NAMPTMEN1KMT2AEPHX2CCR3
SCHEMBL6827780 0.86 EPHX2 (0.53) SMN1; SMN2NPC1RAB9ATSHRMEN1
SCHEMBL6825042 0.86 MEN1 (0.43) SMN1; SMN2NPC1RAB9AHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004087643-A1 DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME PROMEDITECH INC. (KR) 2004-10-14 WO claimed