Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 4/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822302 | 0.89 | KMT2A (0.40) | MEN1KMT2APKMSMN1; SMN2NPC1 | |
| SCHEMBL7064914 | 0.88 | POLB (0.39) | POLBMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7068433 | 0.88 | POLB (0.38) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL6825458 | 0.87 | KLK7 (0.39) | MEN1KMT2AMAPTSMN1; SMN2MMP1 | |
| SCHEMBL6825522 | 0.87 | POLB (0.39) | POLBMAPT | |
| SCHEMBL6822147 | 0.87 | SMN1; SMN2 (0.41) | MEN1KMT2APOLBSMN1; SMN2CCR3 | |
| SCHEMBL6825283 | 0.86 | KMT2A (0.42) | MEN1KMT2APKMSMN1; SMN2NPC1 | |
| SCHEMBL6822393 | 0.85 | SLC6A9 (0.42) | SLC6A9 | |
| SCHEMBL6825485 | 0.84 | RAB9A (0.43) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6825386 | 0.84 | TP53 (0.38) | MEN1KMT2APOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087643-A1 | DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME | PROMEDITECH INC. (KR) | 2004-10-14 | — | — | WO | claimed |