Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827891 | 0.90 | NPC1 (0.44) | EPHX2EPHX1POLBMEN1KMT2A | |
| SCHEMBL6825042 | 0.90 | MEN1 (0.43) | EPHX2EPHX1POLBMEN1KMT2A | |
| SCHEMBL6825283 | 0.89 | KMT2A (0.42) | EPHX2EPHX1MEN1KMT2ANPC1 | |
| SCHEMBL6822406 | 0.86 | KMT2A (0.49) | KMT2ATSHR | |
| SCHEMBL6822147 | 0.86 | SMN1; SMN2 (0.41) | EPHX2EPHX1POLBMEN1KMT2A | |
| SCHEMBL6827756 | 0.86 | NPC1 (0.46) | POLBMEN1LMNAKMT2ANPC1 | |
| SCHEMBL6825386 | 0.85 | TP53 (0.38) | POLBMEN1LMNAKMT2ARAB9A | |
| SCHEMBL6825485 | 0.85 | RAB9A (0.43) | MEN1LMNAKMT2ANPC1RAB9A | |
| SCHEMBL6824982 | 0.83 | RAB9A (0.41) | LMNAKMT2ANPC1RAB9AUSP30 | |
| SCHEMBL6825911 | 0.83 | TP53 (0.38) | POLBMEN1LMNAKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087643-A1 | DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME | PROMEDITECH INC. (KR) | 2004-10-14 | — | — | WO | claimed |
| WO-2004087643-A1 | DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME | PROMEDITECH INC. (KR) | 2004-10-14 | — | — | WO | disclosed |