SCHEMBL6822181

SCHEMBL6822181

O=C(O)C(Cc1ccc(O)cc1)NS(=O)(=O)Cc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 3/20 0.63
ITGA2B P08514 2/20 0.63
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
MMP2 P08253 6/20 0.55
MMP9 P14780 4/20 0.55
ADAMTS4 O75173 1/20 0.55
ITGAV P06756 1/20 0.54
MME P08473 1/20 0.53
SLC1A3 P43003 1/20 0.52
SLC1A2 P43004 1/20 0.52
SLC1A1 P43005 1/20 0.52
ACE P12821 1/20 0.50
ADAMTS5 Q9UNA0 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6822184 1.00 ITGB3 (0.63) ITGB3ITGA2BMEN1KMT2AL3MBTL1
SCHEMBL6093215 0.93 ITGB3 (0.67) ITGB3ITGA2BMMP2MMP9ADAMTS4
SCHEMBL5502396 0.93 ITGB3 (0.67) ITGB3ITGA2BMMP2MMP9ADAMTS4
SCHEMBL6668234 0.93 ITGB3 (0.67) ITGB3ITGA2BMMP2MMP9ADAMTS4
SCHEMBL7087170 0.87 ITGB3 (0.65) ITGB3ITGA2BMMP2MMP9ADAMTS4
SCHEMBL2213584 0.87 ITGB3 (0.65) ITGB3ITGA2BMMP2MMP9ADAMTS4
SCHEMBL7087164 0.87 ITGB3 (0.65) ITGB3ITGA2BMMP2MMP9ADAMTS4
SCHEMBL27695660 0.86 ITGB3 (0.60) ITGB3ITGA2BMMP2MMP9ADAMTS4
SCHEMBL3266667 0.84 MEN1 (0.60) ITGB3ITGA2BMEN1KMT2AL3MBTL1
SCHEMBL28873252 0.83 ITGB3 (0.58) ITGB3ITGA2BMMP2MMP9ADAMTS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US disclosed
EP-4269119-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS Sanko Co., Ltd. (JP) 2023-11-01 EP disclosed
WO-2022145400-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS 三光株式会社 2022-07-07 WO disclosed
EP-3342599-B1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO LTD (JP) 2021-06-16 EP disclosed
CN-108025574-B Thermal recording medium 三光株式会社 2019-04-16 CN disclosed
US-10086634-B2 Heat-sensitive recording material SANKO CO., LTD. (JP) 2018-10-02 US disclosed
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO., LTD. (JP) 2018-07-12 US disclosed
EP-3342599-A1 HEAT-SENSITIVE RECORDING MATERIAL Sanko Co., Ltd. (JP) 2018-07-04 EP disclosed
WO-2004020402-A1 SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE DE NOVO PHARMACEUTICALS LIMITED (GB) 2004-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL ASIC1, SCN1A, NPR1 ITGB3 4191/4885ITGA2B 4381/4885MEN1 830/4885
US-10086634-B2 Heat-sensitive recording material ASIC1, SCN1A, NPR1 ITGB3 4145/4885ITGA2B 4365/4885MEN1 812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.