SCHEMBL6822386

SCHEMBL6822386

CC(C)(C)[C@H](NC(=O)Nc1cc(F)ccc1F)C(=O)N(CC(=O)NO)CC1CCCC1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.36
PKM P14618 2/20 0.36
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 1/20 0.35
GRK2 P25098 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MMP2 P08253 7/20 0.35
MMP3 P08254 4/20 0.35
CCR3 P51677 2/20 0.35
BMP1 P13497 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
HTT P42858 1/20 0.34
MMP1 P03956 2/20 0.34
PYGL P06737 1/20 0.34
MMP9 P14780 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825963 0.89 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1MEN1KMT2AMMP2
SCHEMBL6822301 0.89 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1MEN1KMT2AMMP2
SCHEMBL6923744 0.89 MAPT (0.37) POLBMAPTALDH1A1L3MBTL1MEN1
SCHEMBL6822126 0.88 POLB (0.37) POLBPKMMAPTSMN1; SMN2ALDH1A1
SCHEMBL6822378 0.87 MAPT (0.37) POLBMAPTL3MBTL1
SCHEMBL6825450 0.87 KLK7 (0.40) POLBMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL6827598 0.86 PKM (0.37) POLBPKMMAPTSMN1; SMN2ALDH1A1
SCHEMBL6822141 0.86 RAB9A (0.42) POLBMAPTSMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL6923411 0.86 ALDH1A1 (0.42) MAPTSMN1; SMN2ALDH1A1L3MBTL1KMT2A
SCHEMBL6825276 0.86 MEN1 (0.43) PKMMAPTSMN1; SMN2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004087643-A1 DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME PROMEDITECH INC. (KR) 2004-10-14 WO claimed
WO-2004087643-A1 DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME PROMEDITECH INC. (KR) 2004-10-14 WO disclosed