Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825635 | 0.80 | L3MBTL1 (0.61) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL3483132 | 0.79 | EPHX2 (0.59) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL20679552 | 0.78 | RNF4 (0.59) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28909551 | 0.78 | POLB (0.62) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL572726 | 0.78 | GAA (0.56) | ALDH1A1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9515517 | 0.78 | GAA (0.57) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9428604 | 0.77 | POLB (0.57) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3170705 | 0.77 | MEN1 (0.50) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11141499 | 0.77 | MAPT (0.51) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4104480 | 0.77 | MEN1 (0.75) | POLBALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103819409-A | Preparation method of 5-difluoromethoxy-2-mercapto-1H-benzimidazole | SHENYANG MANWEI CHEMICAL CO LTD | 2014-05-28 | — | — | CN | claimed |
| WO-2004092142-A1 | AN IMPROVED PROCESS FOR MANUFACTURE OF SUBSTITUTED BENZIMIDAZOLES | IPCA LABORATORIES LIMITED (IN) | 2004-10-28 | — | — | WO | claimed |
| CN-103819409-A | Preparation method of 5-difluoromethoxy-2-mercapto-1H-benzimidazole | SHENYANG MANWEI CHEMICAL CO LTD | 2014-05-28 | — | — | CN | disclosed |