Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909551 | 0.85 | POLB (0.62) | POLBMAPTAPOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL11162349 | 0.84 | TSHR (0.56) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5952262 | 0.83 | MEN1 (0.61) | POLBMAPTAPOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL9842891 | 0.83 | TP53 (0.60) | POLBMAPTAPOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL20679552 | 0.82 | RNF4 (0.59) | POLBMAPTAPOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL11427058 | 0.81 | MAPT (0.61) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL593172 | 0.80 | MAPT (0.74) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1117828 | 0.80 | L3MBTL1 (0.69) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4118526 | 0.79 | MAPT (0.66) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21695331 | 0.78 | ALDH1A1 (0.58) | POLBMAPTAPOBEC3AAPOBEC3GALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328907-A | Treatment of allograft rejection in mammals and antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1994-07-12 | — | — | US | disclosed |
| US-5108999-A | For treating inflammation, autoimmune disease or allograft rejection in mammals | SYNTEX (U.S.A.) INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-5001124-A | 4-isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-03-19 | — | — | US | disclosed |