Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704886 | 1.00 | MMP13 (0.56) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6694949 | 0.96 | MMP13 (0.49) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6703411 | 0.83 | MMP13 (0.56) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6697107 | 0.78 | MMP13 (0.60) | MMP13MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL6698919 | 0.78 | CNR2 (0.53) | MMP13MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6704369 | 0.77 | MEN1 (0.50) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6699569 | 0.76 | MMP13 (0.57) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6696589 | 0.73 | MMP13 (0.56) | MMP13MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6698933 | 0.72 | MMP13 (0.49) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6297353 | 0.72 | MMP13 (1.00) | MMP13SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014916-A1 | PYRIMIDINE FUSED BICYCLIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |