Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704886 | 0.96 | MMP13 (0.56) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6822798 | 0.96 | MMP13 (0.56) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6699569 | 0.80 | MMP13 (0.57) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6697107 | 0.79 | MMP13 (0.60) | MMP13MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6703411 | 0.78 | MMP13 (0.56) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6704369 | 0.78 | MEN1 (0.50) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6698933 | 0.75 | MMP13 (0.49) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6704202 | 0.73 | MMP13 (0.57) | MMP13MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL6698919 | 0.72 | CNR2 (0.53) | MMP13MEN1KMT2AHPGDLMNA | |
| SCHEMBL6702609 | 0.71 | MMP13 (0.46) | MMP13MEN1KMT2ARXFP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040038994-A1 | Pyrimidine fused bicyclic metalloproteinase inhibitors | WILSON MICHAEL WILLIAM (US) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038994-A1 | Pyrimidine fused bicyclic metalloproteinase inhibitors | MMP9, MMP1, MMP2 | MMP13 13/4885MEN1 4003/4885KMT2A 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.