Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.36 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.36 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819055 | 0.89 | F10 (0.44) | — | |
| Hydrochloric Acid SCHEMBL6841506 | 0.88 | F10 (0.44) | — | |
| SCHEMBL6820142 | 0.88 | CYP2C9 (0.39) | CYP2C9CYP2C19HTR2BMAPK14SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6818983 | 0.82 | F9 (0.43) | KLKB1LRRK2MET | |
| SCHEMBL3000890 | 0.77 | F9 (0.45) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6841650 | 0.76 | F9 (0.45) | SMN1; SMN2 | |
| SCHEMBL6834989 | 0.76 | SMN1; SMN2 (0.38) | KLKB1CYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL7124454 | 0.72 | MET (0.45) | LRRK2MET | |
| SCHEMBL7160217 | 0.70 | P2RX4 (0.44) | METSCN9A | |
| SCHEMBL2103319 | 0.70 | PTGER1 (0.48) | CYP2C9SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077729-A1 | New carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-04-22 | — | — | US | disclosed |
| WO-2004013115-A2 | CARBOXAMIDES, PRODUCTION AND USE THEREOF AS MEDICAMENTS____ | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077729-A1 | New carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | F2, F11, F12 | KLKB1 1564/4885CYP2C9 50/4885CYP2C19 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.