Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 5/20 | 0.36 |
| ▸ | KLK1 | P06870 | 5/20 | 0.36 |
| ▸ | KLK6 | Q92876 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820142 | 0.85 | CYP2C9 (0.39) | SMN1; SMN2NPSR1NPY2RMAPTMAPK14 | |
| SCHEMBL2995346 | 0.85 | F10 (0.44) | SMN1; SMN2NPSR1HSD11B1 | |
| Hydrochloric Acid SCHEMBL7524480 | 0.84 | F10 (0.43) | SMN1; SMN2NPSR1HSD11B1 | |
| SCHEMBL6823073 | 0.76 | KLKB1 (0.36) | SMN1; SMN2MAPK14METCYP2C9CYP2C19 | |
| SCHEMBL3000890 | 0.73 | F9 (0.45) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6841650 | 0.73 | F9 (0.45) | SMN1; SMN2 | |
| SCHEMBL7525875 | 0.72 | F10 (0.47) | SMN1; SMN2PLGKMT2AHSD11B1TSHR | |
| Hydrochloric Acid SCHEMBL7526160 | 0.72 | F10 (0.46) | SMN1; SMN2PLGKMT2AHSD11B1TSHR | |
| SCHEMBL7528831 | 0.71 | F10 (0.46) | SMN1; SMN2PLGKMT2AHSD11B1TSHR | |
| SCHEMBL6819736 | 0.70 | F10 (0.43) | PLGKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077729-A1 | New carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077729-A1 | New carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | F2, F11, F12 | SMN1; SMN2 2115/4885NPSR1 1173/4885PLG 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.