SCHEMBL6823540

SCHEMBL6823540

O=c1c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2oc2cccc([N+](=O)[O-])c12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 2/20 0.47
CSNK2B P67870 2/20 0.47
CSNK2A1 P68400 2/20 0.47
CSNK2A3 Q8NEV1 1/20 0.47
MAPT P10636 4/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
GAA P10253 1/20 0.44
GPR35 Q9HC97 1/20 0.42
CYP19A1 P11511 3/20 0.42
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 3/20 0.40
LMNA P02545 2/20 0.40
EGFR P00533 1/20 0.40
MAOA P21397 1/20 0.40
NPC1 O15118 1/20 0.40
HSP90AA1 P07900 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11134174 0.85 MEN1 (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT
SCHEMBL9182503 0.84 CYP19A1 (0.56) CSNK2A2CSNK2BCSNK2A1MAPTMEN1
SCHEMBL9180139 0.82 MAPT (0.54) CSNK2A2CSNK2BCSNK2A1MAPTMEN1
SCHEMBL30424337 0.80 ALDH1A1 (0.49) MAPTMEN1KMT2AGPR35CYP19A1
SCHEMBL77405 0.80 ALDH1A1 (0.49) MAPTMEN1KMT2AGPR35CYP19A1
SCHEMBL11661116 0.80 ALDH1A1 (0.51) MAPTMEN1KMT2AGPR35CYP19A1
SCHEMBL2338077 0.80 MEN1 (0.58) CSNK2A2CSNK2BCSNK2A1MAPTMEN1
SCHEMBL4324926 0.76 MAOA (0.60) CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT
SCHEMBL17819622 0.76 CSNK2A2 (0.48) CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT
SCHEMBL9188650 0.72 MEN1 (0.51) CSNK2A2CSNK2BCSNK2A1CSNK2A3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1271259-B1 Image forming apparatus and process cartridge therefor RICOH CO LTD (JP) 2013-11-20 EP disclosed
CN-100414440-C Organophotoreceptor with charge transport compound with hydrazone groups SAMSUNG ELECTRONICS CO LTD (KR) 2008-08-27 CN disclosed
CN-100401195-C Photosensitive body with transferred electron compound salt for electronic photography SAMSUNG ELECTRONICS CO LTD (KR) 2008-07-09 CN disclosed
CN-1567097-A Organophotoreceptor with charge transport compound with hydrazone groups SAMSUNG ELECTRONICS CO LTD (KR) 2005-01-19 CN disclosed
CN-1510526-A Photosensitive body with transferred electron compound salt for electronic photography ���ǵ�����ʽ���� 2004-07-07 CN disclosed
US-6741821-B2 Image forming apparatus, and process cartridge for use in image forming apparatus RICOH COMPANY, LTD. (JP) 2004-05-25 US disclosed
US-20030035660-A1 Image forming apparatus, and process cartridge for use in image forming apparatus RICOH COMPANY, LTD. (JP) 2003-02-20 US disclosed
EP-1271259-A1 Image forming apparatus and process cartridge therefor Ricoh Company, Ltd. (JP) 2003-01-02 EP disclosed
CN-1122015-A M-phenylenediamine derivative and electrophoto-sensitive material using the same SANDA IND CO LTD (JP) 1996-05-08 CN disclosed
EP-0448309-B1 Image-forming process and magnetic developing system for use in carrying out the same MITA INDUSTRIAL CO LTD (JP) 1994-12-07 EP disclosed
US-5171652-A Using magnetic brush of toner and carrier, adjusting flux density distribution of developing sleeve; reducing fog density; electrophotography MITA INDUSTRIAL CO., LTD. (JP) 1992-12-15 US disclosed
EP-0448309-A2 Image-forming process and magnetic developing system for use in carrying out the same MITA INDUSTRIAL CO., LTD. (JP) 1991-09-25 EP disclosed
US-4716220-A CHARGE CARRIER GENERATING MATERIALS RICOH CO., LTD. (JP) 1987-12-29 US disclosed
EP-0094079-B1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITA INDUSTRIAL CO. LTD. (JP) 1986-09-03 EP disclosed
US-4540643-A Tetrazonium salt compounds, novel disazo compounds, method for the production thereof and disazo compound-containing electrophotographic elements RICOH CO., LTD. (JP) 1985-09-10 US disclosed
US-4535044-A Photosensitive material for electrophotography containing photosensitive layer incorporating pentakisazo pigment MITA INDUSTRIAL CO., LTD. (JP) 1985-08-13 US disclosed
EP-0094079-A1 Photosensitive material for electrophotography MITA INDUSTRIAL CO. LTD. (JP) 1983-11-16 EP disclosed