SCHEMBL4324926

SCHEMBL4324926

O=c1c2ccccc2oc2cccc([N+](=O)[O-])c12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.60
ALDH1A1 P00352 3/20 0.55
MAPT P10636 3/20 0.55
KDM4E B2RXH2 1/20 0.55
GLA P06280 1/20 0.55
CYP3A4 P08684 1/20 0.55
HPGD P15428 1/20 0.55
PGAM1 P18669 1/20 0.55
CASP1 P29466 1/20 0.55
CASP7 P55210 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
HSD17B10 Q99714 1/20 0.55
LMNA P02545 2/20 0.52
GAA P10253 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
MGAM O43451 1/20 0.50
SI P14410 1/20 0.50
MGAM2 Q2M2H8 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31116911 0.88 MAPT (0.56) MAOAALDH1A1MAPTKDM4EGLA
SCHEMBL580015 0.88 MAPT (0.56) MAOAALDH1A1MAPTKDM4EGLA
SCHEMBL9180139 0.83 MAPT (0.54) ALDH1A1MAPTLMNAGAAMEN1
SCHEMBL9188650 0.82 MEN1 (0.51) MAOAALDH1A1MAPTKDM4EGLA
SCHEMBL3385902 0.82 MAOA (0.57) MAOAALDH1A1MAPTKDM4EGLA
SCHEMBL7479878 0.82 LMNA (0.53) ALDH1A1MAPTKDM4EHPGDHSD17B10
SCHEMBL17819622 0.80 CSNK2A2 (0.48) MAOAALDH1A1MAPTKDM4ECYP3A4
SCHEMBL3198329 0.80 PIK3CD (0.51) ALDH1A1MAPTLMNAGAAMEN1
SCHEMBL17706811 0.79 ALDH1A1 (0.58) MAOAALDH1A1MAPTLMNAGAA
SCHEMBL27535436 0.76 MAOA (0.51) MAOAALDH1A1MAPTKDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115448914-A Xanthone derivative, preparation method thereof and nitrile benzoxazine derivative containing xanthone structure 电子科技大学 2022-12-09 CN claimed
US-5176854-A Xanthone Derivatives HITACHI, LTD. (JP) 1993-01-05 US claimed
US-4687722-A SILICON WITH HYDROGEN AND CARBON CANON KABUSHIKI KAISHA (JP) 1987-08-18 US claimed
US-4501808-A CARBONIUM OR SULFONIUM COMPOUND; OPTICAL RECORDING MEDIA CANON KABUSHIKI KAISHA (JP) 1985-02-26 US claimed
CN-119514131-A Gas-steam combined cycle flue gas denitration optimal operation method 华能南京燃机发电有限公司 2025-02-25 CN disclosed
CN-117420731-A Negative photosensitive composition and pattern forming method 东京应化工业株式会社 2024-01-19 CN disclosed
CN-116018558-A Negative photosensitive resin composition, pattern forming method and laminated film 三亚普罗股份有限公司 2023-04-25 CN disclosed
CN-115448914-A Xanthone derivative, preparation method thereof and nitrile benzoxazine derivative containing xanthone structure 电子科技大学 2022-12-09 CN disclosed
US-8658433-B2 Dye compounds as photoactive agents MALLINCKRODT LLC (US) 2014-02-25 US disclosed
EP-2666058-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE Ricoh Company Ltd. (JP) 2013-11-27 EP disclosed
WO-2012099181-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-07-26 WO disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
US-5176854-A Xanthone Derivatives HITACHI, LTD. (JP) 1993-01-05 US disclosed
US-5173489-A α,α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DUPONT MERCK PHARMACEUTICAL CO. (US) 1992-12-22 US disclosed
US-4902701-A Tetrazolyl substituted tricyclic compounds and pharmacological compositions thereof BURROUGHS WELCOME CO. (US) 1990-02-20 US disclosed
EP-0315140-A2 Non-linear optical device HITACHI, LTD. (JP) 1989-05-10 EP disclosed
EP-0311010-A2 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1989-04-12 EP disclosed
US-4687722-A SILICON WITH HYDROGEN AND CARBON CANON KABUSHIKI KAISHA (JP) 1987-08-18 US disclosed
EP-0093381-B1 TRICYCLIC COMPOUNDS, PREPARATION, USE AND INTERMEDIATES THE WELLCOME FOUNDATION LIMITED (GB) 1986-07-23 EP disclosed
EP-0093381-A1 Tricyclic compounds, preparation, use and intermediates THE WELLCOME FOUNDATION LIMITED (GB) 1983-11-09 EP disclosed