Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823539 | 0.87 | OPRK1 (0.73) | MEN1KMT2AOPRK1L3MBTL1 | |
| SCHEMBL6823902 | 0.86 | OPRK1 (0.54) | MEN1KMT2AOPRK1 | |
| SCHEMBL6820560 | 0.86 | MEN1 (0.78) | MEN1KMT2AOPRK1L3MBTL1 | |
| SCHEMBL30201364 | 0.81 | MEN1 (0.64) | MEN1KMT2AOPRK1 | |
| SCHEMBL17946338 | 0.81 | KMT2A (0.80) | MEN1KMT2A | |
| SCHEMBL12677187 | 0.81 | SMN1; SMN2 (0.61) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL24950981 | 0.81 | MEN1 (0.63) | MEN1KMT2AOPRK1 | |
| SCHEMBL3871391 | 0.81 | CCR2 (0.53) | — | |
| SCHEMBL30201342 | 0.81 | MEN1 (0.63) | MEN1KMT2AOPRK1 | |
| SCHEMBL3871395 | 0.81 | CCR2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | disclosed |