Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.47 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823638 | 0.86 | MEN1 (0.71) | OPRK1MEN1KMT2A | |
| SCHEMBL17946338 | 0.79 | KMT2A (0.80) | MEN1KMT2ADRD4SLC6A12SLC6A13 | |
| SCHEMBL6823764 | 0.75 | TAS1R3 (0.56) | MEN1KMT2A | |
| SCHEMBL11175035 | 0.75 | DRD2 (0.78) | OPRK1DRD4 | |
| SCHEMBL7374289 | 0.72 | L3MBTL1 (0.74) | OPRK1KMT2A | |
| SCHEMBL6823539 | 0.72 | OPRK1 (0.73) | OPRK1MEN1KMT2A | |
| SCHEMBL6820560 | 0.72 | MEN1 (0.78) | OPRK1MEN1KMT2A | |
| SCHEMBL20797832 | 0.70 | CHRM2 (0.55) | — | |
| SCHEMBL20811168 | 0.70 | CHRM2 (0.55) | — | |
| SCHEMBL9198349 | 0.70 | CCKBR (0.77) | MEN1KMT2ADRD4SLC6A12SLC6A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | disclosed |