Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR1E | P28566 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963572 | 0.69 | LMNA (0.39) | LMNATHRBPOLBMAPTALDH1A1 | |
| SCHEMBL5963903 | 0.67 | LMNA (0.40) | LMNATHRBMAPTALDH1A1CYP2C19 | |
| SCHEMBL3955088 | 0.58 | MAPT (0.62) | LMNATHRBPOLBMAPTALDH1A1 | |
| SCHEMBL23407869 | 0.58 | POLB (0.51) | LMNAPOLBMAPTALDH1A1EPHX1 | |
| SCHEMBL10753297 | 0.57 | MAPT (0.65) | LMNAPOLBMAPTALDH1A1KDM4E | |
| SCHEMBL20898621 | 0.57 | NPSR1 (0.57) | LMNAPOLBMAPTALDH1A1CYP2C19 | |
| SCHEMBL10804640 | 0.56 | POLB (0.74) | LMNAPOLBMAPTALDH1A1HTT | |
| SCHEMBL8278996 | 0.56 | ALDH1A1 (0.62) | LMNATHRBPOLBMAPTALDH1A1 | |
| Diethylamine SCHEMBL10531982 | 0.56 | ALDH1A1 (0.57) | POLBMAPTALDH1A1GAAKDM4E | |
| SCHEMBL11334025 | 0.55 | POLB (0.55) | LMNAPOLBMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326851-B1 | SUBSTITUTED DIPEPTIDES AS GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2004-06-30 | — | — | EP | claimed |