Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.52 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | RGS4 | P49798 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086333 | 0.93 | CCR2 (0.55) | CCR2PTGS2HDAC1HDAC2HDAC8 | |
| SCHEMBL6084959 | 0.90 | MEN1 (0.49) | CCR2PTGS2HDAC1HDAC2HDAC8 | |
| SCHEMBL6817364 | 0.87 | CCR2 (0.52) | CCR2HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL6826249 | 0.86 | CCR2 (0.51) | CCR2HTTRGS4RGS8 | |
| SCHEMBL6085466 | 0.85 | CCR2 (0.67) | CCR2PTGS2PTGDR2MEN1HTT | |
| SCHEMBL7067218 | 0.83 | PTGS2 (0.47) | CCR2PTGS2HDAC1HDAC2HDAC8 | |
| SCHEMBL9959205 | 0.81 | MEN1 (0.56) | CCR2PTGS2HDAC1HDAC2HDAC8 | |
| SCHEMBL9958540 | 0.81 | BRD4 (0.48) | CCR2PTGS2HDAC1HDAC2HDAC8 | |
| SCHEMBL9958735 | 0.81 | KDM4E (0.50) | CCR2PTGS2HDAC1HDAC2HDAC8 | |
| SCHEMBL9959670 | 0.81 | HDAC1 (0.45) | CCR2PTGS2HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |