Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820288 | 0.93 | HTR7 (0.43) | HTR7UTS2RKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6821042 | 0.85 | KDM4E (0.45) | HTR7UTS2RKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6920050 | 0.85 | HTR7 (0.45) | HTR7UTS2RKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5768071 | 0.83 | HTR6 (0.43) | HTR7ALDH1A1 | |
| SCHEMBL6820963 | 0.82 | KDM4E (0.46) | HTR7UTS2RKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3560720 | 0.81 | MAPT (0.41) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6821026 | 0.80 | KDM4E (0.41) | HTR7UTS2RKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6922481 | 0.80 | HTR7 (0.49) | HTR7KDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7063772 | 0.79 | HTR7 (0.45) | HTR7UTS2RKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3557838 | 0.78 | HTR7 (0.43) | HTR7UTS2RKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |