Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820288 | 0.90 | HTR7 (0.43) | HTR7KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7063772 | 0.85 | HTR7 (0.45) | HTR7KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6823917 | 0.85 | HTR7 (0.43) | HTR7KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3555783 | 0.83 | HTR7 (0.40) | HTR7KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6922481 | 0.83 | HTR7 (0.49) | HTR7KDM4EALDH1A1SMN1; SMN2HTR1B | |
| SCHEMBL6821042 | 0.80 | KDM4E (0.45) | HTR7KDM4EALDH1A1SMN1; SMN2UTS2R | |
| SCHEMBL6821035 | 0.79 | HTR6 (0.52) | HTR7HTR1BHTR6 | |
| SCHEMBL6820963 | 0.78 | KDM4E (0.46) | HTR7KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6820274 | 0.78 | HTR7 (0.39) | HTR7KDM4EALDH1A1LMNATDP1 | |
| SCHEMBL6821104 | 0.76 | ALDH1A1 (0.39) | HTR7KDM4EALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |