Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154224 | 0.89 | ESR1 (0.37) | ESR1MAPTKDM4ETDP1HTR7 | |
| SCHEMBL6820282 | 0.87 | TDP1 (0.42) | ESR1MAPTKDM4ETDP1LTA4H | |
| SCHEMBL6917019 | 0.83 | ESR1 (0.48) | ESR1MAPTKDM4ETDP1HTR7 | |
| SCHEMBL3556742 | 0.82 | KDM4E (0.43) | MAPTKDM4ETDP1HTR7CSF1R | |
| SCHEMBL6817304 | 0.81 | ESR1 (0.43) | ESR1KDM4ETDP1HTR7LTA4H | |
| SCHEMBL6820268 | 0.81 | UTS2R (0.42) | ESR1MAPTKDM4EHTR7DRD1 | |
| SCHEMBL6820250 | 0.79 | ESR1 (0.47) | ESR1MAPTKDM4ETDP1HTR7 | |
| SCHEMBL6820710 | 0.79 | KDM4E (0.41) | ESR1KDM4ETDP1ALDH1A1KCNH2 | |
| SCHEMBL3565496 | 0.79 | HTR6 (0.37) | MAPTKDM4ETDP1HTR7DRD2 | |
| SCHEMBL3562676 | 0.78 | HTR6 (0.39) | MAPTKDM4ETDP1CSF1RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |