Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820713 | 0.89 | TDP1 (0.41) | TDP1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6823932 | 0.87 | ESR1 (0.38) | TDP1KDM4EPTGDR2MAPTALDH1A1 | |
| SCHEMBL6820693 | 0.86 | UTS2R (0.46) | TDP1KDM4EPTGDR2MAPTALDH1A1 | |
| SCHEMBL6821061 | 0.83 | TDP1 (0.53) | TDP1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6821022 | 0.81 | TDP1 (0.41) | TDP1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6817320 | 0.81 | TDP1 (0.47) | TDP1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6820272 | 0.79 | KDM4E (0.46) | TDP1KDM4EMEN1KMT2AGAA | |
| SCHEMBL3562439 | 0.78 | HTR6 (0.45) | TDP1KDM4EMAPTALDH1A1DRD2 | |
| SCHEMBL6817497 | 0.78 | TDP1 (0.52) | TDP1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7154224 | 0.76 | ESR1 (0.37) | TDP1KDM4EMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |