Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821103 | 0.92 | ESR1 (0.50) | ESR1TDP1MAPTKMT2AALDH1A1 | |
| SCHEMBL6817304 | 0.91 | ESR1 (0.43) | ESR1TDP1KDM4EESR2MDM2 | |
| SCHEMBL7067775 | 0.88 | UTS2R (0.42) | ESR1TDP1MAPTL3MBTL1MAT2A | |
| SCHEMBL6820250 | 0.87 | ESR1 (0.47) | ESR1TDP1MEN1GAAMAPT | |
| SCHEMBL6922144 | 0.87 | ESR1 (0.51) | ESR1MAPTKMT2A | |
| SCHEMBL6821061 | 0.86 | TDP1 (0.53) | ESR1TDP1MEN1GAAMAPT | |
| SCHEMBL6823932 | 0.83 | ESR1 (0.38) | ESR1TDP1MAPTALDH1A1KDM4E | |
| SCHEMBL7154224 | 0.82 | ESR1 (0.37) | ESR1TDP1GAAMAPTALDH1A1 | |
| SCHEMBL3555919 | 0.81 | KDM4E (0.45) | MEN1GAAMAPTKMT2AMAT2A | |
| SCHEMBL6817279 | 0.79 | UTS2R (0.42) | ESR1MEN1KMT2AMAT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |