Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | FPR1 | P21462 | 4/20 | 0.42 |
| ▸ | FPR2 | P25090 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6823485 | 0.80 | DPP4 (0.47) | DPP4DPP8FPR1FPR2KDM1A | |
| SCHEMBL5116905 | 0.72 | DPP7 (0.49) | DPP4DPP8KDM1AARFAAH | |
| SCHEMBL2579137 | 0.70 | SMN1; SMN2 (0.61) | DPP4DPP8ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL5111851 | 0.69 | PTGES (0.46) | ARFAAHF2PRSS1 | |
| SCHEMBL16825436 | 0.69 | FNTA (0.53) | DPP4DPP8CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL14289388 | 0.68 | DPP7 (0.53) | DPP4DPP8KDM1AARFAAH | |
| SCHEMBL4423185 | 0.68 | NPC1 (0.64) | — | |
| Hydrochloric Acid SCHEMBL5107306 | 0.68 | DPP7 (0.52) | DPP4DPP8KDM1AARFAAH | |
| Hydrochloric Acid SCHEMBL5107311 | 0.68 | DPP7 (0.52) | DPP4DPP8KDM1AARFAAH | |
| SCHEMBL4423181 | 0.67 | ALDH1A1 (0.49) | DPP4DPP8FPR1FPR2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067522-A1 | AZAPHENYLALANINE DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | LEK PHARMACEUTICALS D.D. (SI) | 2004-08-12 | — | — | WO | disclosed |