Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 14/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824422 | 0.91 | HTR7 (0.42) | HTR7UTS2RCCR5HTR1ADRD4 | |
| SCHEMBL6824418 | 0.89 | HTR7 (0.40) | HTR7UTS2RDRD4MEN1KMT2A | |
| SCHEMBL6381981 | 0.89 | HTR7 (0.49) | HTR7UTS2RCCR5HTR1ADRD4 | |
| SCHEMBL6823920 | 0.85 | PTK2 (0.45) | HTR7UTS2RHTR1AMEN1KMT2A | |
| SCHEMBL7351045 | 0.84 | HTR7 (0.47) | HTR7UTS2RHTR1AMEN1KMT2A | |
| SCHEMBL6824127 | 0.83 | HTR7 (0.45) | HTR7UTS2RHTR1A | |
| SCHEMBL6824544 | 0.83 | HTR7 (0.40) | HTR7UTS2RDRD4MEN1KMT2A | |
| SCHEMBL6823392 | 0.82 | HTR7 (0.49) | HTR7UTS2RCCR5HTR1ADRD4 | |
| SCHEMBL6462162 | 0.81 | MCHR1 (0.43) | HTR7UTS2RHTR1AMEN1KMT2A | |
| SCHEMBL6462165 | 0.81 | MCHR1 (0.43) | HTR7UTS2RHTR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | claimed |
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | disclosed |