Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | GABRP | O00591 | 2/20 | 0.57 |
| ▸ | GABRD | O14764 | 2/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.57 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.57 |
| ▸ | GABRE | P78334 | 2/20 | 0.57 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.57 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.57 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.57 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.57 |
| ▸ | PRKDC | P78527 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827255 | 0.83 | SMN1; SMN2 (0.56) | PRKDCMAOBALDH1A1MAPTCYP3A4 | |
| SCHEMBL6827893 | 0.81 | PDE4A (0.57) | ALDH1A1MAPTCYP3A4KDM4EHPGD | |
| SCHEMBL6829505 | 0.80 | EGFR (0.62) | EGFRPRKDCMAOBALDH1A1MAPT | |
| SCHEMBL6824581 | 0.78 | EGFR (0.58) | EGFRPRKDCMAOBALDH1A1MAPT | |
| SCHEMBL28887784 | 0.78 | EGFR (0.58) | EGFRPRKDCMAOBALDH1A1MAPT | |
| SCHEMBL24425880 | 0.77 | EGFR (1.00) | EGFRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL6823834 | 0.77 | GABRP (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6827090 | 0.73 | TNKS (0.50) | PRKDCMAOBALDH1A1KCNH2TNKS | |
| SCHEMBL3922778 | 0.73 | ESR1 (0.51) | EGFRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21801147 | 0.73 | GABRP (0.63) | EGFRGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |