Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824255 | 0.83 | EGFR (0.62) | SMN1; SMN2KDM4ECYP3A4ALDH1A1HPGD | |
| SCHEMBL6827354 | 0.82 | CYP3A4 (0.60) | SMN1; SMN2KDM4ECYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6827203 | 0.82 | ALDH1A1 (0.56) | SMN1; SMN2KDM4ECYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6827893 | 0.77 | PDE4A (0.57) | SMN1; SMN2KDM4ECYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6823834 | 0.77 | GABRP (0.51) | SMN1; SMN2KDM4ECYP3A4MAPK1ALDH1A1 | |
| SCHEMBL2991933 | 0.72 | KCNA3 (0.61) | SMN1; SMN2KDM4ECYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6827426 | 0.72 | MAPT (0.55) | SMN1; SMN2KDM4ECYP3A4MAPK1ALDH1A1 | |
| 7,3'-Dimethoxyflavone SCHEMBL718068 | 0.72 | KDM4E (1.00) | SMN1; SMN2KDM4ECYP3A4MAPK1ALDH1A1 | |
| SCHEMBL13802274 | 0.71 | ALDH1A1 (0.54) | SMN1; SMN2KDM4ECYP3A4MAPK1ALDH1A1 | |
| SCHEMBL2648845 | 0.71 | CYP3A4 (0.57) | SMN1; SMN2CYP3A4ALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |