Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654419 | 0.81 | CYP1B1 (0.61) | PDE4AABCB1ALDH1A1MAPK1KDM4E | |
| SCHEMBL6824255 | 0.81 | EGFR (0.62) | ABCB1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL6827686 | 0.79 | ALDH1A1 (0.57) | PDE4AABCB1ALDH1A1MAPK1KDM4E | |
| SCHEMBL3125629 | 0.78 | PDE4A (0.72) | PDE4AABCB1ALDH1A1MAPK1KDM4E | |
| SCHEMBL6827255 | 0.77 | SMN1; SMN2 (0.56) | ALDH1A1MAPK1KDM4EMAPTMEN1 | |
| SCHEMBL6827426 | 0.76 | MAPT (0.55) | ALDH1A1MAPK1KDM4EMAPTMEN1 | |
| SCHEMBL15265120 | 0.75 | CSNK2A2 (0.80) | ABCB1ALDH1A1MAPK1KDM4EMAPT | |
| SCHEMBL27915929 | 0.73 | PDE4A (0.59) | PDE4AABCB1ALDH1A1MAPK1KDM4E | |
| SCHEMBL9618242 | 0.72 | PDE4A (0.62) | PDE4AABCB1ALDH1A1MAPK1KDM4E | |
| SCHEMBL16788881 | 0.72 | PDE4A (0.62) | PDE4AABCB1ALDH1A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |