Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 2/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818413 | 1.00 | PDE1A (0.38) | PDE1APDE1BPDE1CADORA1BACE1 | |
| SCHEMBL6818764 | 1.00 | PDE1A (0.38) | PDE1APDE1BPDE1CADORA1BACE1 | |
| SCHEMBL6818744 | 0.95 | BACE1 (0.39) | PDE1APDE1BPDE1CADORA1BACE1 | |
| SCHEMBL6822534 | 0.86 | FGFR1 (0.40) | ADORA1NSD3IGF1RMAPK1DPP4 | |
| SCHEMBL6818477 | 0.83 | ADORA1 (0.38) | ADORA1BACE1MAPK1 | |
| SCHEMBL7365779 | 0.82 | ADORA1 (0.39) | ADORA1NSD3CREBBPIGF1RMAPK1 | |
| SCHEMBL7365777 | 0.82 | ADORA1 (0.39) | ADORA1NSD3CREBBPIGF1RMAPK1 | |
| SCHEMBL6822006 | 0.79 | ADORA1 (0.46) | ADORA1IGF1RMAPK1 | |
| SCHEMBL6821959 | 0.77 | ADORA1 (0.42) | PDE1APDE1BPDE1CADORA1IGF1R | |
| SCHEMBL6821431 | 0.77 | ADORA1 (0.51) | ADORA1IGF1RMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110763-A1 | Pyrazolopyridine compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110763-A1 | Pyrazolopyridine compound and pharmaceutical use thereof | ADRB1, ADRA1D, ADRB3 | PDE1A 1716/4885PDE1B 748/4885PDE1C 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.