Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365777 | 1.00 | ADORA1 (0.39) | ADORA1DPP4IL4I1KCNH2KDM4C | |
| SCHEMBL7367704 | 0.94 | ADORA1 (0.40) | ADORA1DPP4KCNH2IGF1RDPP8 | |
| SCHEMBL7366165 | 0.91 | ADORA2A (0.38) | ADORA1KDM4CMEN1CASP1CASP7 | |
| SCHEMBL7364072 | 0.89 | DPP4 (0.43) | DPP4KCNH2KDM4CDPP8DPP9 | |
| SCHEMBL7367701 | 0.87 | ADORA1 (0.42) | ADORA1DPP4KCNH2IGF1RDPP8 | |
| SCHEMBL7371146 | 0.86 | ADORA1 (0.41) | ADORA1DPP4KCNH2IGF1RDPP8 | |
| SCHEMBL7367570 | 0.85 | NSD3 (0.48) | ADORA1DPP4KCNH2IGF1RDPP8 | |
| SCHEMBL6824299 | 0.82 | PDE1A (0.38) | ADORA1DPP4IGF1RDPP8DPP9 | |
| SCHEMBL6818413 | 0.82 | PDE1A (0.38) | ADORA1DPP4IGF1RDPP8DPP9 | |
| SCHEMBL6818764 | 0.82 | PDE1A (0.38) | ADORA1DPP4IGF1RDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244669-A1 | PYRAZOLOPYRAZINES AND THEIR USE AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001040230-A1 | PYRAZOLOPYRAZINES AND THEIR USE AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-07 | — | — | WO | disclosed |