SCHEMBL5838985

SCHEMBL5838985

C=C(C)C(=O)O[Si](C)(C)CCCC

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
ALDH1A1 P00352 3/20 0.38
THRB P10828 2/20 0.37
CES1 P23141 2/20 0.31
THRA P10827 1/20 0.31
CES2 O00748 2/20 0.31
PAOX Q6QHF9 1/20 0.31
HPGD P15428 1/20 0.31
ACHE P22303 1/20 0.31
EPHX1 P07099 1/20 0.31
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7185265 0.92 TSHR (0.55) TSHRALDH1A1THRBCES1THRA
SCHEMBL27941728 0.92 TSHR (0.55) TSHRALDH1A1THRBCES1THRA
SCHEMBL7185234 0.92 TSHR (0.55) TSHRALDH1A1THRBCES1THRA
SCHEMBL15826448 0.88 TSHR (0.47) TSHRALDH1A1THRBTHRACES2
SCHEMBL2308683 0.88 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL7191288 0.84 TSHR (0.48) TSHRALDH1A1THRBCES1THRA
SCHEMBL5314563 0.82 ALDH1A1 (0.37) TSHRALDH1A1THRB
SCHEMBL1525545 0.82 TSHR (0.50) TSHRALDH1A1THRBCES1THRA
SCHEMBL476046 0.81 ALDH1A1 (0.43) TSHRALDH1A1CES1CES2PAOX
SCHEMBL7507608 0.81 TSHR (0.55) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060276113-A1 Polishing cloth, polishing apparatus and method of manufacturing semiconductor devices HIRABAYASHI HIDEAKI 2006-12-07 US disclosed
EP-1487844-A1 PROCESS FOR THE PREPARATION OF TRIHYDROCARBYLSILYLATED CARBOXYLATE MONOMERS SIGMA COATINGS B.V. (NL) 2004-12-22 EP disclosed
US-20040236130-A1 Process for the preparation of trialkylsilated carboxylate monomers, the obatined trialkylsilated carboxylate monomers and their use in anti-fouling coatings SIGMA COATINGS B.V. (NL) 2004-11-25 US disclosed
EP-1389214-A1 PROCESS FOR THE PREPARATION OF TRIALKYLSILYLATED CARBOXYLATE MONOMERS, THE OBTAINED TRIALKYLSILYLATED CARBOXYLATE MONOMERS AND THEIR USE IN ANTI-FOULING COATINGS SIGMA COATINGS B.V. (NL) 2004-02-18 EP disclosed
US-6630079-B2 Bis(2- pyridinethiol-1-oxide) copper salt, does not exert any adverse influence on the storage stability or antifouling effect, and the effect of the salt does not change by the coating with an acrylic resin API CORPORATION (JP) 2003-10-07 US disclosed
EP-1080640-B1 COATED BIS(2-PYRIDINETHIOL-1-OXIDE)COPPER SALT API CORP (JP) 2003-09-10 EP disclosed
WO-2003072585-A1 PROCESS FOR THE PREPARATION OF TRIHYDROCARBYLSILYLATED CARBOXYLATE MONOMERS SIGMA COATINGS B.V. (NL) 2003-09-04 WO disclosed
EP-1340763-A1 Process for the preparation of trihydrocarbylsilylated unsaturated carboxylate monomers SIGMA COATINGS B.V. (NL) 2003-09-03 EP disclosed
US-20030124085-A1 Coated bis (2-pyridinethiol-1-oxide) copper salt API CORPORATION (JP) 2003-07-03 US disclosed
US-6544440-B1 Antifouling active ingredient for a coating for the bottom of a ship, which is safe during handling; rosin coated; biocides API CORPORATION (JP) 2003-04-08 US disclosed
EP-1295888-A1 Process for the preparation of trialkylsilylated carboxylate monomers, the obtained trialkylsilylated carboxylate monomers and their use in antifouling coatings SIGMA COATINGS B.V. (NL) 2003-03-26 EP disclosed
WO-2002094838-A1 PROCESS FOR THE PREPARATION OF TRIALKYLSILYLATED CARBOXYLATE MONOMERS, THE OBTAINED TRIALKYLSILYLATED CARBOXYLATE MONOMERS AND THEIR USE IN ANTI-FOULING COATINGS SIGMA COATINGS B.V. (NL) 2002-11-28 WO disclosed
EP-1260513-A1 Process for the preparation of trialkylsilylated carboxylate monomers, the obtained trialkylsilylated carboxylate monomers and their use in antifouling coatings SIGMA COATINGS B.V. (NL) 2002-11-27 EP disclosed
EP-1227111-A1 TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF Yoshitomi Fine Chemicals, Ltd. (JP) 2002-07-31 EP disclosed
EP-1080640-A1 COATED BIS(2-PYRIDINETHIOL 1-OXIDE) COPPER SALT Yoshitomi Fine Chemicals, Ltd. (JP) 2001-03-07 EP disclosed
EP-0626620-B1 Method for forming resist pattern NIPPON PAINT CO LTD (JP) 1996-10-09 EP disclosed
EP-0626620-A1 Method for forming resist pattern Nippon Paint Co., Ltd. (JP) 1994-11-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040236130-A1 Process for the preparation of trialkylsilated carboxylate monomers, the obatined trialkylsilated carboxylate monomers and their use in anti-fouling coatings ACMSD, OR10J3, CFD TSHR 3555/4885ALDH1A1 223/4885THRB 2910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.