Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 7/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962606 | 0.94 | TSHR (0.70) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL27832270 | 0.93 | TSHR (0.59) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL27812601 | 0.90 | TSHR (0.64) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL8962461 | 0.89 | TSHR (0.62) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL2168904 | 0.88 | TSHR (0.56) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL19206369 | 0.86 | TSHR (0.68) | TSHRTHRBALDH1A1TDP1POLB | |
| Hexane SCHEMBL28941486 | 0.85 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL8962684 | 0.83 | TSHR (0.68) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL476606 | 0.82 | TSHR (0.56) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL22322552 | 0.82 | TSHR (0.56) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102040224-B | Hydrophobic core-shell silica particle, hollow silica particle, and manufacturing methods thereof | ADEKA CORP | 2015-07-15 | — | — | CN | disclosed |
| CN-102040224-A | Hydrophobic core-shell silica particle, hollow silica particle, and manufacturing methods thereof | ADEKA CORP | 2011-05-04 | — | — | CN | disclosed |
| US-5554706-A | LOW TEMPERATURE LIQUID CRYSTALS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0695770-A1 | COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-02-07 | — | — | EP | disclosed |