Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HK1 | P19367 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822028 | 0.90 | PTGS2 (0.58) | PTGS2MAPTHK1HTTHKDC1 | |
| SCHEMBL6921953 | 0.85 | PTGS2 (0.54) | PTGS2TP53CCR2GRIK1GRIK2 | |
| SCHEMBL6085769 | 0.83 | PTGS2 (0.57) | PTGS2TP53HTTCCR2GRIK1 | |
| SCHEMBL7067218 | 0.80 | PTGS2 (0.47) | PTGS2TP53MAPTHK1HTT | |
| SCHEMBL6824400 | 0.77 | MAPT (0.52) | PTGS2MAPTHK1HTTHKDC1 | |
| SCHEMBL8762468 | 0.77 | CCR2 (0.55) | PTGS2NTRK1CCR2ACLY | |
| SCHEMBL8762443 | 0.76 | NTRK1 (0.48) | PTGS2NTRK1CCR2ACLY | |
| SCHEMBL8762218 | 0.75 | TSHR (0.60) | PTGS2MAPTHTTNTRK1 | |
| SCHEMBL8762327 | 0.75 | F10 (0.62) | PTGS2NTRK1 | |
| SCHEMBL6820278 | 0.75 | PTGS2 (0.53) | PTGS2CCR2GRIK1GRIK2ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |