Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | CCR2 | P41597 | 8/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6085769 | 0.92 | PTGS2 (0.57) | PTGS2CCR2TP53CNR2GRIK1 | |
| SCHEMBL6820278 | 0.90 | PTGS2 (0.53) | PTGS2CCR2GRIK1GRIK2ACLY | |
| SCHEMBL6824420 | 0.85 | PTGS2 (0.59) | PTGS2CCR2TP53GRIK1GRIK2 | |
| SCHEMBL6086162 | 0.81 | PTGS2 (0.71) | PTGS2CCR2CNR2KDM4EHPGD | |
| SCHEMBL8648612 | 0.81 | GRIK1 (0.65) | PTGS2CCR2GRIK1GRIK2ACLY | |
| SCHEMBL6823866 | 0.80 | CCR2 (0.52) | PTGS2CCR2 | |
| SCHEMBL8762380 | 0.79 | CCR2 (0.72) | CCR2ACLY | |
| SCHEMBL28384928 | 0.78 | CCR2 (0.64) | PTGS2CCR2TP53 | |
| SCHEMBL8763020 | 0.77 | CCR2 (0.47) | PTGS2CCR2ACLY | |
| SCHEMBL6817364 | 0.77 | CCR2 (0.52) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |