Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824617 | 0.87 | NPC1 (0.45) | MCHR1 | |
| SCHEMBL6827280 | 0.87 | ABCB1 (0.46) | MCHR1 | |
| SCHEMBL6827367 | 0.85 | MCHR1 (0.53) | MCHR1HDAC8HDAC6 | |
| SCHEMBL6829426 | 0.85 | MCHR1 (0.64) | MCHR1HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL6918913 | 0.85 | HTR1F (0.50) | ACKR3 | |
| SCHEMBL6829437 | 0.85 | ALDH1A1 (0.46) | MCHR1 | |
| SCHEMBL6824937 | 0.85 | MEN1 (0.46) | MCHR1HDAC8 | |
| SCHEMBL6918359 | 0.84 | MCHR1 (0.43) | MCHR1 | |
| SCHEMBL6924507 | 0.84 | THRB (0.48) | MCHR1 | |
| SCHEMBL6824487 | 0.83 | ALDH1A1 (0.46) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004010943-A2 | SUBSTITUTED BENZANILIDES AS MODULATORS OF THE CCR5 RECEPTOR | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-05 | — | — | WO | claimed |
| WO-2004010943-A2 | SUBSTITUTED BENZANILIDES AS MODULATORS OF THE CCR5 RECEPTOR | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |