Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | CD38 | P28907 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3773526 | 0.76 | CA2 (0.61) | CHRNB2CHRNA4CA2MTNR1AMAPT | |
| SCHEMBL6824957 | 0.75 | CHRNB2 (0.67) | CHRNB2CHRNA4CA2MTNR1AMAPT | |
| SCHEMBL1386337 | 0.74 | MTNR1A (0.76) | CHRNB2CHRNA4CA2MTNR1AMAPT | |
| SCHEMBL29145305 | 0.71 | MTNR1A (0.62) | CHRNB2CHRNA4CA2MTNR1AMAPT | |
| SCHEMBL3817884 | 0.71 | CA2 (0.70) | CHRNB2CHRNA4CA2MTNR1AMAPT | |
| SCHEMBL22323341 | 0.70 | MEN1 (0.66) | CHRNB2CHRNA4CA2MTNR1AMAPT | |
| SCHEMBL6824633 | 0.70 | CHRNB2 (0.60) | CHRNB2CHRNA4CA2MTNR1AMAPT | |
| SCHEMBL3767060 | 0.70 | CA2 (0.61) | CHRNB2CHRNA4CA2MTNR1AMAPT | |
| SCHEMBL15539428 | 0.70 | CHRNB2 (0.60) | CHRNB2CHRNA4CA2MAPTMEN1 | |
| SCHEMBL6824966 | 0.70 | CHRNB2 (0.67) | CHRNB2CHRNA4CA2MTNR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099127-A1 | NOVEL COMPOUNDS AS KINASE INHIBITORS | NOVO NORDISK A/S (DK) | 2004-11-18 | — | — | WO | disclosed |