Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 16/20 | 0.74 |
| ▸ | CA12 | O43570 | 15/20 | 0.74 |
| ▸ | CA1 | P00915 | 10/20 | 0.73 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.61 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.61 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.61 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.61 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821696 | 0.92 | CA9 (0.64) | CA9CA12CA1APEX1CA2 | |
| SCHEMBL6825234 | 0.86 | CA9 (0.66) | CA9CA12CA1CA2RAB9A | |
| SCHEMBL6349448 | 0.84 | CA9 (0.67) | CA9CA12CA1CA2RAB9A | |
| SCHEMBL6821697 | 0.81 | CA12 (0.61) | CA9CA12CA1 | |
| SCHEMBL17947763 | 0.81 | CA9 (0.90) | CA9CA12CA1CA2RAB9A | |
| SCHEMBL6827172 | 0.78 | CA12 (0.63) | CA9CA12CA1RAB9ASMN1; SMN2 | |
| Probenecid SCHEMBL1034640 | 0.77 | CA9 (1.00) | CA9CA12CA1CA2RAB9A | |
| Probenecid SCHEMBL3663 | 0.77 | CA9 (1.00) | CA9CA12CA1CA2RAB9A | |
| SCHEMBL2028671 | 0.77 | DHODH (0.86) | CA12CA1RAB9ASMN1; SMN2 | |
| SCHEMBL6825144 | 0.77 | CA9 (0.72) | CA9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099127-A1 | NOVEL COMPOUNDS AS KINASE INHIBITORS | NOVO NORDISK A/S (DK) | 2004-11-18 | — | — | WO | disclosed |