SCHEMBL6349448

SCHEMBL6349448

CCCN(CCC)S(=O)(=O)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)O)cc1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 15/20 0.67
CA12 O43570 14/20 0.67
CA1 P00915 9/20 0.67
SERPINE1 P05121 5/20 0.58
CA2 P00918 3/20 0.56
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
SLC22A6 Q4U2R8 1/20 0.56
SLC22A8 Q8TCC7 1/20 0.56
ABCC2 Q92887 1/20 0.56
SLC22A12 Q96S37 1/20 0.56
UGT1A7 Q9HAW7 1/20 0.56
SLC22A11 Q9NSA0 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6349618 0.85 SERPINE1 (0.53) CA9CA12CA1SERPINE1CA2
SCHEMBL6824792 0.84 CA9 (0.74) CA9CA12CA1CA2RAB9A
Hydrochloric Acid SCHEMBL6346555 0.84 SERPINE1 (0.52) CA9CA12CA1SERPINE1CA2
Hydrochloric Acid SCHEMBL6358891 0.84 SERPINE1 (0.52) CA9CA12CA1SERPINE1CA2
SCHEMBL6357624 0.83 CA12 (0.52) CA9CA12CA1SERPINE1RAB9A
SCHEMBL6825234 0.83 CA9 (0.66) CA9CA12CA1CA2RAB9A
SCHEMBL6821696 0.81 CA9 (0.64) CA9CA12CA1CA2RAB9A
SCHEMBL2885883 0.80 CA9 (0.60) CA9CA12CA1CA2SMN1; SMN2
SCHEMBL2892747 0.80 CA9 (0.58) CA9CA12CA1CA2RAB9A
SCHEMBL2893220 0.78 CA9 (0.55) CA9CA12CA1CA2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050113450-A1 Antibacterial agents PHARMACIA & UPJOHN COMPANY 2005-05-26 US claimed
US-20050113450-A1 Antibacterial agents PHARMACIA & UPJOHN COMPANY 2005-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113450-A1 Antibacterial agents CLPP, SPOUT1, SAMHD1 CA9 2085/4885CA12 3717/4885CA1 4266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.