Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718465 | 0.89 | MEN1 (0.55) | BRD4ALDH1A1KMT2ALMNATHRB | |
| SCHEMBL8345848 | 0.85 | CTSS (0.56) | BRD4ALDH1A1KMT2ALMNATHRB | |
| SCHEMBL6727015 | 0.85 | CYP1A2 (0.53) | ALDH1A1KMT2ALMNATHRBMEN1 | |
| SCHEMBL6827177 | 0.85 | KMT2A (0.52) | ALDH1A1KMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL6718886 | 0.81 | BRD4 (0.62) | BRD4ALDH1A1KMT2ALMNATHRB | |
| SCHEMBL6718828 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL6726608 | 0.78 | MAPT (0.51) | ALDH1A1KMT2ALMNATHRBMEN1 | |
| SCHEMBL6715851 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL6715528 | 0.78 | HSD17B10 (0.53) | ALDH1A1KMT2ALMNAMEN1TP53 | |
| SCHEMBL6726586 | 0.78 | MAPT (0.51) | ALDH1A1LMNASMN1; SMN2TP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |