Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 5/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 6/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169066 | 0.88 | MAPT (0.58) | MAPTKMT2AKCNN4CYP1A2HTT | |
| SCHEMBL28091404 | 0.81 | KMT2A (0.52) | MAPTKMT2AKIF11KCNN4CES2 | |
| SCHEMBL5056428 | 0.79 | MAPT (0.46) | MAPTKMT2AKIF11KCNN4MIF | |
| SCHEMBL20268402 | 0.79 | ADRA2A (0.43) | MAPTKMT2AKIF11MIFCES2 | |
| SCHEMBL20268404 | 0.79 | ADRA2A (0.43) | MAPTKMT2AKIF11MIFCES2 | |
| SCHEMBL5852218 | 0.77 | MAPT (0.47) | MAPTKMT2AKIF11KCNN4CYP1A2 | |
| SCHEMBL6821772 | 0.75 | CES1 (0.50) | KMT2ACES2CES1NPC1RAB9A | |
| SCHEMBL7268810 | 0.74 | KCNN4 (0.70) | KMT2AKIF11KCNN4MIFCYP1A2 | |
| SCHEMBL2392133 | 0.74 | KIF11 (0.44) | MAPTKMT2AKIF11KCNN4MIF | |
| SCHEMBL6824958 | 0.73 | KIF11 (0.48) | MAPTKMT2AKIF11KCNN4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |